Publications

Gladwyne, PA 1903Gao ZQ, Gao ZP, Fields JZ, Boman BM. Co-transfection of MDR1 and MRP Antisense RNAs Abolishes the Drug Resistance in Multidrug-resistant Human Lung Cancer Cells.  Anticancer Research 18:3073-3076, 1998



Gao ZQ, Gao ZP, Fields JZ, Boman BM.  Tumor-specific expression of anti-mdr1 ribozyme selectively restores chemosensitivity in multidrug-resistant colon-adenocarcinoma cells.  Intl. J. Ca. 82:346-52, 1999.



Boman BM,  Fields JZ., Hereditary Cancer Syndromes. In The Molecular Basis of Human Cancer WB Coleman & GJ Tsongalis (eds.) The Humana Press, Inc., Totowa, NJ. pp. 159-185, 2001.



Boman BM, Fields JZ, Bonham-Carter O, Runquist OA.  Computer Modeling Implicates Stem Cell Overproduction  in Colon Cancer Initiation.  Cancer Research 61: 8406-9, 2001.



Zhang T, Otevrel T, Gao ZQ, Gao ZP, Ehrlich SM, Fields, JZ, Boman BM.  Evidence that APC regulates Survivin expression: A possible mechanism contributing to the stem cell origin of colon cancer. Cancer Res. 61: 8664-7, 2001



Gao ZQ, Gao ZP, Fields JZ, Boman BM.  Development of cross-resistance to Tamoxifen in Raloxifene-treated breast carcinoma cells.  Anticancer Research 22:1379-2384, 2002.



Zhang T, Fields JZ, Ehrlich SM, Boman BM. The Chemopreventive Agent Sulindac Attenuates Expression of the Anti-Apoptotic Protein Survivin in Colorectal Carcinoma Cells. J Pharm Exp Therap. 308:434-437, 2004.



Fields JZ, Gao ZP, Gao ZQ, Lewis M, Maimonis P, Harvey J, Lynch HT, Boman BM. Immunoassay predicts both DNA mismatch repair (MMR) and APC germline mutations in lymphocytes from patients at risk for hereditary colorectal cancer (CRC).  J Lab Clin Med 143:59-66, 2004.



Boman BM, Zhang T, Fields JZ. Correspondence: Evidence that APC Regulates Survivin Expression: A Possible Mechanism Contributing to the Stem Cell Origin of Colon Cancer. Cancer Res 64:776-779, 2004.



Boman BM, Walters R, Fields JZ, Kovatich AJ, Zhang T, Isenberg GA, Goldstein SD, Palazzo JP, Colonic crypt changes during adenoma development in FAP: Immunohistochemical evidence for expansion of the crypt base cell population Am J Pathol 165:1489-1498, 2004.



Boman BM, Wicha M, Fields JZ, Runquist O. Symmetric Division of Cancer Stem Cells – A Key Mechanism In Tumor Growth That Should Be Targeted In Future Therapeutic Approaches. Clin Pharmacol Therap 81:893-898, 2007.



Boman BM, Fields JZ, Cavanaugh KL, Gujetter A, Runquist OA. How dysregulated colonic crypt dynamics cause stem cell overpopulation and initiate colon cancer. Cancer Research  6:3304-3313, 2008.

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